麻豆国产

Every year, the 麻豆国产 recognises 10 outstanding research achievements from the previous 12 months. In evaluating and making the final selection of the 10 most outstanding achievements, the Research and Development Committee鈥檚 working group principally takes into account their international impact, their comprehensiveness, how relevant they are to the wider professional audience and the general public, and their applicability. All the proposals were assessed equally, regardless of the discipline, and regardless of whether they involved pure or applied research.

Protein complexes from edible mushrooms as sustainable protection of potatoes against plant pests

Authors: Dr Anna Coll, Prof. Dr Kristina Gruden, Dr Maja Grundner, Asst. Prof. Dr Tja拧a Lukan, Dr Anastasija Panevska, Dr Marko Petek, Karmen Poga膷ar, Senior Research Associate Dr Jaka Razinger, Prof. Dr Kristina Sep膷i膰, Research Associate Primo啪 沤igon, MSc

Proposed by: Biotechnical Faculty, 麻豆国产

The Colorado potato beetle is one of the most wide-spread plant pests worldwide. The damage it causes is measured in billions of US dollars. It is controlled using chemical insecticides, which can accumulate in the environment and be toxic to non-target organisms and humans. An additional problem is the development of insect resistance to insecticides.

This paper describes a strategy for the development of genetically modified potato plants expressing the insecticidal protein complexes PlyA2/PlyB from the edible oyster mushroom. The transformed plants are effectively protected against Colorado potato beetle larvae, with no difference in plant morphology, growth or tuber yield compared to non-transformed plants.

PlyA2/PlyB show a number of advantages over other insecticides. Their action is linked to their binding to a membrane lipid found only in insects, and they are therefore non-toxic to non-target arthropods and mammals. They break down rapidly in the environment and are immediately degraded by mammalian digestive enzymes. Gene expression analysis of beetles surviving PlyA2/PlyB supplementation showed no signs of specific adaptation to the action of the complex.

The results of the research, whose authors are exclusively collaborators of Slovenian scientific research institutions, are protected by an international patent application and are opening the way for the development of environmentally friendly bioinsecticides, safe from resistance development, offering new possibilities for solving the problems faced by modern agriculture.

Source

Poga膷ar K, Grundner M, 沤igon P, Coll A, Panevska A, Lukan T, Petek M, Razinger J, Gruden K, Sep膷i膰 K. Protein complexes from edible mushrooms as a sustainable potato protection against coleopteran pests. Plant Biotechnol J. 2024 Sep;22(9):2518-2529. doi: 10.1111/pbi.14365. Epub 2024 May 10. PMID: 38733093; PMCID: PMC11331795.

From crisis to prosperity: how coordinated economic policies shape our future

Author: Prof. Dr Miroslav Verbi膷

Proposed by: School of Economics and Business, 麻豆国产

In today's challenging global environment, understanding the impact of financial markets and economic policies on prosperity is more important than ever. This collection of three papers, published in prestigious international journals with high impact factors, sheds light on how financial market distress, unexpected changes in crediting, and coordinated monetary and fiscal policies affect business investment and overall economic stability in Slovenia and the euro area.

The papers show how the difficulty companies face in obtaining finances in times of financial uncertainty can increase the intensity of the downturn. They reveal that banks become more cautious not only because of profit concerns, but above all because of increased financial risks, a finding that is particularly relevant in light of recent global financial pressures and the need for resilient banking practices. The papers also analyse how central bank actions and government spending and tax decisions affect economic growth and inflation. While raising interest rates can help control inflation, it can also slow economic growth. On the other hand, appropriate fiscal policies can provide the economy with immediate support, underlining the importance of well-coordinated economic policy measures.

Together, the contributions offer valuable guidance for policy makers confronted with the complexity of the global environment. They underline the need to ensure that companies have access to the financing they need and suggest tailoring policies to each country's circumstances. By combining detailed analysis at the company level with broader economic trends, they improve our understanding of contemporary economic challenges and offer practical solutions to promote stability and growth.

Sources

Zabavnik, D., Verbi膷, M. (2023). The Effects of Financial Frictions on Slovenian Companies: A Panel VAR Approach. Finance Research Letters, 58 (C), 104563.

Zabavnik, D., Verbi膷, M. (2024). Unravelling the Credit Market Shocks and Investment Dynamics: A Theoretical and Empirical Perspective. International Review of Financial Analysis, 94, 103283.

Rant, V., Puc, A., 膶ok, M., Verbi膷, M. (2024). Macroeconomic Impacts of Monetary and Fiscal Policy in the Euro Area in Times of Shifting Policies: A SVAR Approach. Finance Research Letters, 64, 105406.

Party System Changes and Challenges to Democracy: Slovenia in a Comparative Perspective

Author: Prof. Dr Danica Fink Hafner

Proposed by: Faculty of Social Sciences, 麻豆国产

In her book, Danica Fink Hafner analyses the link between the stability of the party system and democracy. Based on a thorough theoretical framing, longitudinal research on the case of Slovenia and internationally comparative empirical research, she identifies the factors that influence the decline of democracy. Slovenia experienced a rapid but limited democratic decline in the period between March 2019 and June 2022. This is in contrast to the better-known cases of Hungary and Poland, where such a decline took place gradually over a longer period through several electoral cycles. Danica Fink Hafner has argued that there is not a single and sufficient factor that causes democratic decline; instead, it results from a complex interplay of factors (party characteristics, other players, broader social and economic factors, and in particular the various crises that allow for the introduction of states of emergency). The work thus fills an important gap in the debate on the study of political parties and processes of de-democratisation. Danica Fink Hafner's book has been published by the internationally renowned Springer Nature and is open-access. It attracted widespread interest immediately after its publication, as reflected in the number of accesses to the book on .

Source

Fink Hafner, Danica. Party system changes and challenges to democracy: Slovenia in a comparative perspective. Cham: Springer Nature. DOI: 

Deep models for regression of brain age as a general diagnostic criterion for neurodegenerative diseases

Authors: Asst. Lara Dular, Prof. Dr Franjo Pernu拧, Assoc. Prof. Dr 沤iga 艩piclin (project leader)

Proposed by: Faculty of Electrical Engineering, 麻豆国产

Prediction of brain age from magnetic resonance (MR) scans of the head and any differences between predicted and chronological age serve as a common biomarker for all diseases with a neurodegenerative effect. In this study, we developed advanced deep learning architectures to regress brain age directly from T1-weighted head MR images and, based on a large, publicly available dataset of healthy adult subjects (18鈥95 years), proposed a standardised protocol for evaluating regression models that includes assessing the accuracy, robustness, reproducibility and temporal consistency of brain age estimates. We demonstrated a favourable impact of advanced preprocessing of T1-weighted MR images on the reproducibility of brain age regression between different MR scanners. Age differences were comparatively evaluated for healthy control groups and affected groups with sleep apnoea, diabetes, multiple sclerosis (MS), Parkinson's disease, mild cognitive impairment and Alzheimer's dementia (AD). Patients with AD and MS showed the largest age differences (up to +6.48 and +4.24 years, respectively), but in all affected groups we observed a trend of decreasing difference with increasing age, suggesting the biased influence of survival, disease progression, therapy and lifestyle adaptation.

The study is reproducible, with publicly released data and software code, and the results have been published in three original scientific articles with an impact factor of Q1.

Sources

Dular, Lara, and 沤iga 艩piclin. 鈥淏ASE: Brain Age Standardized Evaluation.鈥 NeuroImage 285 (1 January 2024): 120469. .

Dular, Lara, Franjo Pernu拧, and 沤iga 艩piclin. 鈥淓xtensive T1-Weighted MRI Preprocessing Improves Generalizability of Deep Brain Age Prediction Models.鈥 Computers in Biology and Medicine 173 (1 May 2024): 108320. .

Dular, Lara and 沤iga 艩piclin. 鈥淎nalysis of Brain Age Gap across Subject Cohorts and Prediction Model Architectures.鈥 Biomedicines 12, no. 9 (September 2024): 2139. .

Dynamics of magnetization at infinite temperature in a Heisenberg spin chain

Authors: Dr Trond I. Andersen, Prof. Dr Toma啪 Prosen (lead author), Dr Eliott Rosenberg, Dr Pedram Roushan (lead author)

Proposed by: Faculty of Mathematics and Physics, 麻豆国产

The study of quantum dynamics 鈥 how quantum systems change over time 鈥 is still a major challenge in science. One theory that addresses this is the 1D Heisenberg model, which describes how spins (small magnets) behave in a one-dimensional chain. Scientists have hypothesised that these dynamics could fit into the Kardar鈥揚arisi鈥揨hang (KPZ) universality class, which describes certain types of growth and propagation in nature. In this study, the researchers used a chain of 46 superconducting qubits (the basic units of quantum computers) to study how magnetisation (a measure of the magnetic field) is transferred across the chain鈥檚 centre. They measured the probability distribution describing the likelihood that the magnetisation will reach a certain value. The first two moments of this distribution showed superdiffusive behaviour, meaning that the magnetisation spreads faster than in normal diffusion, which is a hallmark of KPZ universality. However, the third and fourth moments ruled out the KPZ conjecture and allowed for evaluating other theories. These results highlight the importance of studying higher moments (more than just the mean and variance) in determining dynamic universality classes. This provides insights into universal behaviour in quantum systems and helps in the development of new theories. More generally, this content is a fundamental yet globally extraordinary contribution to the field of quantum mechanics.

Source

Dynamics of magnetization at infinite temperature in a Heisenberg spin chain. Science. 2024, vol. 384, no. 6691, pp. 48鈥53, illustr. ISSN 0036-8075. , DOI: . [COBISS.SI-ID ], [, , ,  until 2 October 2024: number of citations (TC): 5, pure citations (CI): 5, pure citations per author (CIAu): 0.22,  until 23 September 2024: number of citations (TC): 7, pure citations (CI): 7, pure citations per author (CIAu): 0.31]

Project: P1-0402-2019 Matemati膷na fizika; financed by: Slovenian Research and Innovation Agency.

Tunable entangled photon-pair generation in a liquid crystal

Authors: Maria V. Chekhova, Alja啪 Kav膷i膷, Emmanouil Kokkinakis, Matja啪 Humar, Vitaliy Sultanov, Nerea Sebasti谩n Ugarteche

Proposed by: Faculty of Mathematics and Physics, 麻豆国产

Liquid crystals, with their ability to self-assemble, strong response to an electric field and integrability into complex systems, are key materials in light-beam manipulation. The recently discovered ferroelectric nematic liquid crystals also have considerable second-order optical nonlinearity, making them a potential material for nonlinear optics. This work implements spontaneous parametric down-conversion in a ferroelectric nematic liquid crystal and demonstrates electric-field tunable broadband generation of entangled photons, with an efficiency comparable to that of the best nonlinear crystals. The emission rate and polarisation state of photon pairs is markedly varied by applying a few volts or twisting the molecular orientation along the sample. A liquid-crystal source enables a special type of quasi-phase matching, which is based on the molecular twist structure and is therefore reconfigurable for the desired spectral and polarisation properties of photon pairs. Such sources promise to outperform standard nonlinear optical materials in terms of functionality, brightness and the tunability of the generated quantum state. The concepts developed in this work can be extended to complex topological structures, macroscopic devices and multi-pixel tunable quantum light sources. The content is a fundamental contribution at the interdisciplinary intersection of quantum mechanics and soft matter physics of the highest global rank.

Sources

Tunable entangled photon-pair generation in a liquid crystal. Nature: the international weekly journal of science. [Print ed.]. 2024, vol. 631, iss. 8020, pp. 294鈥299, illustr. ISSN 0028-0836. , DOI: . [COBISS.SI-ID ], [, , , ,  until 23 September 2024: number of citations (TC): 3, pure citations (CI): 2, pure citations per author (CIAu): 0.33]

Project: 851143 Intracellular lasers: Coupling of optical resonances with biological processes [Cell-Lasers]; financed by: European Commission;
Project: P1-0099-2022 Fizika mehkih snovi, povr拧in in nanostruktur; financed by: Slovenian Research and Innovation Agency;
Project: P1-0192-2022 Svetloba in snov; financed by: Slovenian Research and Innovation Agency.

Hypereg: a new regenerator for high-frequency solid-liquid heat regeneration

Authors: Prof. Dr Andrej Kitanovski (project leader), Asst. Prof. Dr Katja Klinar, Assoc. Prof. Dr Franc Majdi膷, Dr Jure Mencinger, Asst. Prof. Dr Izidor Sabotin, Dr Urban Tomc, Assoc. Prof. Dr Jo拧ko Valentin膷i膷

Proposed by: Faculty of Mechanical Engineering, 麻豆国产

LAHDE (Laboratory for Refrigeration and District Energy) researchers, in collaboration with other departments at the Faculty of Mechanical Engineering, have invented a new concept for a heat regenerator that allows a several-fold improvement in the power density of the devices in which it is used. Such devices include heat pumps, cooling devices and power generators based on gas or caloric thermodynamic cyclic processes. A regenerator is a heat storage and transfer device made of a solid matrix through which a working fluid oscillates.

The principles behind regenerators have been known for almost 100 years, but they have limited applications. At higher frequencies (i.e. more cycles of oscillation of the fluid flow per temporal interval), pressure losses become excessive and the time interval for heat transfer along the regenerator becomes too short.

The new regenerator concept, called Hypereg, solves the problem of excessive pressure losses and thus extends the use of regenerators to higher operating frequencies. Hypereg is hydraulically separated into several smaller compartments in which the fluid oscillates along the solid (as in a conventional regenerator), and additionally introduces an external fluid flow transverse to these compartments. The coordinated fluid flow in all parts of the Hypereg therefore allows for efficient heat regeneration between the solid and the fluid even at higher frequencies, which in turn allows for a significant increase in the power density of both caloric and gas-cycle devices, which include thermoacoustic and mechanical Stirling technologies.

The Hypereg concept, for which the inventors obtained US and Chinese patents [1], was first published in the paper [2].

Source

[1] Patent: KITANOVSKI, Andrej, TOMC, Urban, KLINAR, Katja, VALENTIN膶I膶, Jo拧ko, MAJDI膶, Franc, SABOTIN, Izidor, MENCINGER, Jure. Method for heat transfer in the embedded structure of a heat regenerator and the design thereof: United States patent US 12,000,663 B2, 2024-06-04. Alexandria: United States Patent and Trademark Office, 2024. [35] f., illustr. . [COBISS.SI-ID ]
patent family: US201917273099A, 2019-09-02; P-2019050018, 2019-09-02; CN112654778B, 2023-08-15; EP3847361A1, 2021-07-14; SI25712A, 2020-03-31; US2021341232A1, 2021-11-04; WO2020050780A1, 2020-03-12

[2] Scientific article: Klinar, K; Kitanovski, A; Law, J Y; Franco, V; Moya, X. Perspectives and Energy Applications of Magnetocaloric, Pyromagnetic, Electrocaloric, and Pyroelectric Materials. Advanced Energy Materials, First published: 30 August 2024, Online Version of Record before inclusion in an issue, 2401739,

Multilingual platform FitBack to support monitoring physical fitness in children and adolescents

Authors: Asst. Prof. Dr Rok Blagus, Prof. Dr Attilio Carraro, Alessandra Colangelo, Assoc. Prof. Dr Tamas Csanyi, Dr Jose J. Gil-Cosano, Asst. Prof. Dr Mikko Huhtiniemi, Dr Laura Joensuu, Prof. Dr Gregor Jurak (project leader), Dr Katalin K盲lbi, Asst. Prof. doc. dr. Bojan Lesko拧ek, Asst. Prof. Dr Jo茫o Magalh茫es, Asst. Prof. Dr Evelin M盲estu, Assoc. Prof. Dr Jarek M盲estu, Assoc. Prof. Dr Ivana Milanovi膰, Asst. Prof. Dr Vladimir Milo拧evi膰, Asst. Prof. Dr Shawnda A. Morrison, Prof. Dr Francisco B. Ortega, Asst. Prof. Dr Marcos Olvera Rojas, Prof. Dr Jonatan R. Ruiz, Assoc. Prof. Dr Maroje Sori膰, Prof. Dr. Gregor Starc, Asst. Prof. Dr Hrvoje Podnar, Prof. Dr Luis B. Sardinha, Dr Giampaolo Santi, Prof. Dr Tuija H. Tammelin, Prof. Dr Grant R. Tomkinson

Proposed by: Faculty of Sports, 麻豆国产

Spremljanje telesne zmogljivosti na ravni posameznika in populacije je prednostna naloga javnega zdravja in izobra啪evanja. Vendar je trenutno v mednarodni praksi le nekaj nacionalnih sistemov za spremljanje telesne zmogljivosti, med njimi pa je vodilna Slovenija. Pod vodstvom Fakultete za 拧port smo zato razvili mednarodno mre啪o in , ki z ve膷 orodji omogo膷a spremljanje telesne zmogljivosti 拧olajo膷ih se otrok. Na podlagi 8 milijonov zbranih podatkov o telesni zmogljivosti evropskih otrok in mladostnikov ter pregleda izsledkov raziskav o vplivu posameznih komponent telesne zmogljivosti na zdravstvene izide smo raziskovalci oblikovali evropske standarde telesne zmogljivosti. Te smo implementirali v interaktivno poro膷ilo, ki omogo膷a takoj拧njo povratno informacijo o telesni zmogljivosti posameznika v primerjavi z zdravstvenim tveganjem in evropskimi vrstniki. Poro膷ilo je podprto tudi z nasveti za izbolj拧anje telesne zmogljivosti in pogovornim robotom.

Za odlo膷evalce smo na podlagi analize obstoje膷ih nacionalnih sistemov razvili priporo膷ila za razvoj sistemov spremljanja telesne zmogljivosti otrok in mladine, opisali primere dobrih praks in pripravili evropski zemljevid telesne zmogljivosti. S tem smo vzpostavili edinstveno mednarodno mre啪o in infrastrukturo, ki jo 啪e uporabljajo v ve膷 dr啪avah.

Sources

Carraro, A., Santi, G., Colangelo, A., M盲estu, J., Milo拧evi膰, V., Morrison, S. A., Olvera-Rojas, M., Podnar, H., & Jurak, G. (2023). Usability evaluation of the international FitBack web portal for monitoring youth fitness. Sport Sciences for Health, 19(4), 1363鈥1373. https://doi.org/10.1007/s11332-023-01117-0

Joensuu, L., Cs谩nyi, T., Huhtiniemi, M., K盲lbi, K., Magalh茫es, J., Milanovi膰, I., Morrison, S. A., Ortega, F. B., Sardinha, L. B., Starc, G., Tammelin, T. H., & Jurak, G. (2024). How to design and establish a national school-based physical fitness monitoring and surveillance system for children and adolescents: A 10-step approach recommended by the FitBack network. Scandinavian Journal of Medicine and Science in Sports, 34(3). https://doi.org/10.1111/sms.14593

Ortega, F. B., Lesko拧ek, B., Blagus, R., Gil-Cosano, J. J., M盲estu, J., Tomkinson, G. R., Ruiz, J. R., M盲estu, E., Starc, G., Milanovi膰, I., Tammelin, T. H., Sori膰, M., Scheuer, C., Carraro, A., Kaj, M., Cs谩nyi, T., Sardinha, L. B., Lenoir, M., Emeljanovas, A., 鈥 Jurak, G. (2023). European fitness landscape for children and adolescents: updated reference values, fitness maps and country rankings based on nearly 8 million test results from 34 countries gathered by the FitBack network. British Journal of Sports Medicine, 57(5), 299鈥310.

What's that smell? A philosophy of the olfactory

Author: Senior Research Associate, Asst. Prof. Dr Simon Hajdini

Proposed by: Faculty of Arts, 麻豆国产

Why is it that Indo-European languages do not have words to directly describe scents, leaving us with no choice but to simply call the smell of a rose sweet? This scholarly monograph, published by one of the most prestigious academic publishers in the world, situates itself at the intersection between philosophy, psychoanalysis and the often neglected sense of smell, in order to put smell at the centre of philosophical critique of traditional conceptions of truth through new readings of both traditional and contemporary philosophical texts, and thus to challenge the established notion of smell as an anti-philosophical sense.

With its innovative interdisciplinary approach to fundamental philosophical questions, its original analyses of modernist fiction and film, and its novel use of natural science research on olfaction in a humanistic context, the monograph places the problem of olfaction at the very heart of cultural life. In doing so, it defends the far-reaching thesis that ontology, civilisation and capitalist economy must be conceived of as waste management. And it is only by following the most philosophically debased sense that we can better understand the central philosophical, psychoanalytical and political questions of truth, sexuality and exploitation.

The work contributes to the reputation and relevance of Slovenian philosophical thought and has a significant impact on current research in the fields of sensorial studies, psychoanalysis, anthropology, political economy, aesthetics and interdisciplinary research in technology. A Spanish translation of the work is forthcoming.

Source

HAJDINI, Simon. What's that smell? : a philosophy of the olfactory. Cambridge (Mass.); London: The MIT Press, cop. 2024. XIV, 200 pages. Short circuits. ISBN 978-0-262-54756-7. [COBISS.SI-ID 183917827] category: 2A (Z, A'', A', A1/2); type of work verified by OSICH points: 160, number of authors: 1.

Membrane nanostructures

Authors: Dr Matev啪 Arko, Vesna Arrigler, Dr Marija Holcar, Asst. Prof. Dr Samo Hudoklin, Prof. Dr Ale拧 Igli膷, Prof. Dr Ksenija Kogej, Prof. Dr Veronika Kralj-Igli膷 (project leader and lead author of the article), Prof. Dr Mateja Erdani-Kreft, Assoc. Prof. Dr Metka Lenassi, Dr Nata拧a Resnik, Prof. Dr Rok Romih, Anna Romolo, Dr Vesna Spasovski, Ur拧ka Zagorc

Proposed by: Faculty of Health Sciences, 麻豆国产

The results so far show that matter and information at the cellular level are transported in the form of nano-sized particles 鈥 extracellular vesicles (EVs). Synthetic nanoparticles (liposomes and their combinations with EVs 鈥 hybridosomes) can actively interfere with this. EVs and hybridosomes can mediate interactions between all living systems and the environment, and are the cornerstone of the One Health concept. Understanding and mastering the properties of these structures and their interactions will lead to advanced solutions in medicine, agriculture, the food industry and environmental sciences. The proposed members of the Laboratory of Clinical Biophysics (LKBF) research group at the UL Faculty of Health Sciences, which brings together collaborators from several UL faculties and colleagues from abroad, have developed a method for preparing hybridosomes from lecithin, spruce needle isolate and glycerol, as reported in [1]. These hybridosomes contained bioactive substances from spruce and achieved yields that facilitate their large-scale application. Veronika Kralj-Igli膷 and Anna Romolo are members of the International Society for Extracellular Vesicles, which collects and disseminates information on EVs at a global level (publication [2]). In the context of their activities in the field of membrane nanostructures, they have also published a paper highlighting the importance of both experimental and theoretical work on membrane nanostructures [3]. With the proposed achievement published in ([1]鈥揫3]), the LKBF ranks among the leading research groups in the field of biophysics of membrane nanostructures.

Sources

Spasovski Vesna, Romolo Anna, Zagorc Ur拧ka, Arrigler Vesna, Kisovec Matic, Bedina Zavec Apolonija, Arko Matev啪, Moln谩r Adrienn, Schlosser Gitta, Igli膷 Ale拧, Kogej Ksenija, Kralj-Igli膷 Veronika. Characterization of nanohybridosomes from lipids and spruce homogenate containing extracellular vesicles. International journal of nanomedicine. [Online ed.]. Feb. 2024, vol. 19, pp. 1709鈥1721, illustr. ISSN 1178-2013. DOI: 10.2147/IJN.S432836. [COBISS.SI-ID 186884099]. IF=8.

Welsh Joshua A, Goberdhan Deborah CI, Lenassi Metka, Witwer KW, et al., Bedina Zavec Apolonija, Holcar Marija, Hudoklin Samo, Kralj-Igli膷 Veronika, Erdani-Kreft Mateja, Mari膰 Ivica, Resnik Nata拧a, Romih Rok, Romolo Anna, Stoka Veronika, et al. Minimal information for studies of extracellular vesicles (MISEV2023) : from basic to advanced approaches. Journal of extracellular vesicles. Feb. 2024, vol. 13, iss. 2, [article no.] e12404, pp. 1鈥84, illustr. ISSN 2001-3078. DOI: 10.1002/jev2.12404. [COBISS.SI-ID 185664003] IF=16, 260/244 pure citations in WoS/Scopus (2 September 2024).

Romolo Anna, Kralj-Igli膷 Veronika. Milestones in Research of Small Cellular Particles. Membrane Modeling and Theoretical Description in Connection with In vitro and Ex vivo processes. Proceedings of Socratic Lectures. 2024; 10: 59鈥68.